PRP-3 Analytical Guard Column Replacement Cartridges (5/pk), Stainless SteelPRP 3 particles come with a larger (300 ) pore size for protein separation. No silanol groups on the resin means no irreversible protein adsorption, giving > 90% analyte recovery. This stable material also allows the use of concentrated acids, chaotropes, and even detergents to minimize problems with protein solubility. PRP 3 Overview The PRP 3 is a reversed phase column optimized for separation of macromolecules such as DNA, RNA oligos, proteins,